Off-Label Drug Use in Pediatrics Appropriate Circumstances for Off-label Drug Prescription After diagnosis, health professionals often begin the treatment regimen with the first line of medication and only resort to off-label drugs following treatment unresponsiveness or worsening of symptoms (Rusz et al., 2021). Selective serotonin reuptake inhibitors (SSRI) like Zoloft (50 mg) may be prescribed […]