How are schizophrenia and bipolar disorder affected by genetic factors? The major psychiatric diseases, schizophrenia, and bipolar disorder have been the subjects of numerous genetic studies. Twins, adoption, and family studies have shown that both disorders aggregate in families. Genetic studies of psychiatric disorders are challenging because these disorders are undoubtedly heterogeneous, reflecting the influence […]
How are genes associated with Alzheimer disease? Alzheimer disease (AD) is responsible for 50% to 80% of cases of progressive cognitive impairment (dementia) among older adults. It affects approximately 1 in 10 individuals older than 65 years of age and 1 in 3 individuals older than 85 years of age. Due to the aging of […]
How are genes associated with susceptibility to alcohol addiction? Alcoholism (now formally termed alcohol use disorder) is diagnosed in approximately 10% of adult males and 3% to 5% of adult females in the United States. The national cost of alcoholism, in terms of lost productivity and direct medical costs, is approximately $250 billion per year. […]
What is the pathophysiology of type 2 diabetes? Type 2 diabetes accounts for more than 90% of all diabetes cases and affects 10% to 20% of the adult populations of many high-income countries. Several features distinguish it from type 1 diabetes. There is always some endogenous insulin production in people with type 2 diabetes, and […]
How does genetics affect type 1 diabetes? The etiology of diabetes mellitus, like other disorders, is complex and not fully understood. Progress is being made in understanding the genetic basis of this disorder, which is a leading cause of blindness, heart disease, and kidney failure. Diabetes is a heterogeneous group of disorders, all characterized by […]
How do genes correlate with cancer? Cancer is the second leading cause of death in the United States. It is well established that many major types of cancer (e.g., breast, colon, prostate, ovarian) cluster strongly in families. Clustering is caused by both inherited genes and shared environmental factors. Numerous cancer-causing genes are being isolated but […]
How do genetic and environmental factors affect blood pressure? Systemic hypertension has a worldwide prevalence of approximately 25% to 30%. It is a key risk factor for heart disease, stroke, and kidney disease. Blood pressure correlations within families indicate that approximately 20% to 40% of the variation in both systolic and diastolic blood pressure is […]
You will prepare an article review aligned with this week’s learning module and readings. Using the UWA Library Databases, you will identify a peer-reviewed empirical research article that includes hypothesis testing. The selected article must be relevant to topics discussed in the weekly readings.
Create a poster presentation to communicate an implementation plan to bridge the gap between the evidence you will research and clinical practice. You have been asked to give a poster presentation based on your work and research on a clinical problem in your practice setting. Chosen topic: Staffing shortages and burnout in hospital settings Identify a clinical problem in your work setting and develop an […]
Create a poster presentation to communicate an implementation plan to bridge the gap between the evidence you will research and clinical practice. You have been asked to give a poster presentation based on your work and research on a clinical problem in your practice setting. Chosen topic: Staffing shortages and burnout in hospital settings Identify a clinical problem in your work setting and develop an […]